Eye Conditions and Treatments

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Diabetic Retinopathy

>Close Introduction

Diabetic retinopathy develops some time before there are any visual symptoms and in the early stages it can only be detected by an examination of the back of the eye performed by a specialist. Routine checks of the back of the eye (screening) is important, because if diagnosed at this early stage, diabetic retinopathy can generally be treated very effectively. Over the past 15 years laser treatment has been shown to be helpful in either stopping the progress of the disease or in maintaining sight. 

As a diabetic it is important to know:

Diabetic retinopathy is the commonest cause of blindness.

The main treatment for diabetic retinopathy is laser treatment.

Retinopathy is usually classified according to the severity which may differ in both eyes.

Non-proliferative retinopathy is the earliest stage in the development of retinopathy. It is unusual before 8-10 years of diabetes. At this stage vision is normal and there is no threat to sight. The presence of diabetic changes of haemorrhage, abnormal blood vessels (microaneurysms) and fatty deposits (exudates) is herald of more severe retinopathy, particularly if the macula is affected (maculopathy). It alerts the doctor to plan more frequent follow up. Once diabetic maculopathy is diagnosed the standard treatments are laser or sometimes injections into the back of the eye.

Proliferative retinopathy The capillaries block and starve the retina of nutrients. In response to this new vessels grow. They either grow in front of the retina on to the back surface of the vitreous, or occasionally onto the iris. The new vessels are fragile and may bleed into the vitreous. This gives rise to floaters, either dots or lines that if severe cloud the vision or cause loss of vision. If vessels grow on the iris they cause an increase in the pressure in the eye and cause severe and painful glaucoma. The new vessels eventually produce scar tissue which may result in a retinal detachment with severe loss of sight. The treatment for glaucoma is often injections into the eye combined with laser treatment. Surgery is usually required for persistent diabetic vitreous haemorrhage or retinal detachment.

>Close Symptoms

Diabetic retinopathy does not usually cause any symptoms until it has reached an advanced stage. In some cases, the only noticeable symptom is a sudden and complete loss of vision (often due to a bleed). This is why regular screening is so important.

Symptoms of diabetic retinopathy include:

  • discoloured spots that ‘float’ in your field of vision (known as floaters),
  • blurred vision due to maculopathy or cataract, which is more common in diabetics
  • vision blocked by patches or streaks due to blood in front of the retina
  • reduced night vision, and most seriously

sudden vision loss due to severe intraocular bleeding or retinal detachment

>Close Causes

Diabetic retinopathy is a complication of diabetes that affects the retina. The retina is the layer at the back of the eye which is sensitive to light and to function properly, light must be able to pass through the eye uninterrupted to reach the retina. Light passes through the cornea, lens and vitreous (a jelly-like substance in the eye) to reach the retina in the same way that light rays pass through the lens of a camera to reach the film. The focused light or images are then relayed to the brain by the optic nerve. The macula is the area of the retina concerned with central detailed vision especially for reading. Diabetes causes the capillaries (tiny blood vessels in the retina) to become blocked, this may then lead to leakage in the central retina (diabetic maculopathy) or result in the growth of the new vessels which may bleed and fill the eye with blood (vitreous haemorrhage). Both conditions are treatable by laser in the early stages but may require surgery.

Can any diabetic develop retinopathy?

Yes. Diabetics of all types: 

  • The young and insulin dependent.
  • Those on diet only.
  • Diabetics on hypoglycaemic tablets.
  • The well controlled can develop it if they have had diabetes long enough.

Is there any way to prevent it?

No. But good diabetic control can slow down the rate of the progression of complications.

You should: 

Control your diet.

Always take your diabetic treatment. NOT taking treatment is harmful.

  • Avoid becoming overweight.
  • Avoid smoking completely
  • Avoid excessive alcohol, but a small amount is fine
  • Have blood pressure checks and treat any hypertension
  • Check your cholesterol level and take tablets to reduce it if high

Improving diabetic control can have an effect on diabetic retinopathy itself, and should be maintained to try to prevent any further deterioration.

Would eye checks have prevented it?

No. They would not have prevented disease but would enable early diagnosis and early treatment and this would benefit your eyesight. Adult Insulin dependent diabetics needs to have their eyes examined every year. Patients diagnosed in childhood should be checked annually following the onset of puberty and diabetic women should be checked several times during pregnancy as this can make the vessels grow. Other diabetics (not on insulin) should have an eye examination every year by their diabetic specialist, GP, ophthalmologist or optician. Sight tests are FREE for diabetics.

HOSPITAL TESTS

What does the eye examination involve?

You will have a sight test (using those familiar charts) and then a full eye examination. Instruments such as an ophthalmoscope and slip lamp are used to give a good view inside the eye. Eye drops are put in your eyes to make the pupils bigger. The ophthalmologist must examine the back of your eye through the dilated pupil. Your vision will be blurred temporarily preventing you from reading and there may be difficulty driving for a few hours. Avoid driving yourself to hospital or the local railway station whenever you come to have your retina examined because your pupils will always need to be dilated.

Will I need any further tests?

Yes: colour photographs taken with a special camera and using ‘flash’. These enable the doctor to see and keep an accurate record of what is going on at the back of the eye. They are kept in your records and can be used for later comparisons.

Fluorescein angiogram.This is a test used for a few patients for one of 3 reasons:

  • To establish the diagnosis.
  • So that the doctor can see the exact area to direct laser treatment.
  • To enable the doctor to see why patients my have lost any vision.

Your pupils will be dilated (as above). A small injection of yellow dye is injected into a vein in your arm. This dye circulates throughout the body and to the retinal blood vessels so that the network of capillaries can be seen. A series of flash photos will be taken while you are sitting at the slit lamp to show the passage of dye through the vessels in the retina. The dye will not leak out of normal capillaries; if it is leaking it means the vessels are diseased or new vessels have developed.

The results and appropriate treatment will be discussed with you. During angiography some 10% of patients will develop nausea and occasionally sickness that soon passes. Allergic reactions rarely occur. The dye has the effect of yellowing the skin for 3-6 hours and urine for 24 hours. Continue to test your urine in the normal way but test your blood sugar as well because the dye may affect the result of the urine test (by turning it dark orange).

>Close Treatment

How will this condition be treated?

Initially by photocoagulation (laser). This procedure focuses a laser beam (high energy light beam) in small bursts onto the damaged retina. There are 2 laser techniques

  • Maculopathy: This requires precise laser treatment around the macula at the centre of the retina to seal the leaking blood vessels.
  • Proliferative: extensive laser treatment to the starved retina is undertaken. The new vessels then shrink and this reduces the chance of haemorrhage. Treatment is usually performed on an outpatient basis and can be lengthy or may need to be repeated. Laser treatment is designed to maintain vision not improve it.

It is highly effective in most patients. Blindness can be prevented in 80-90% of cases.

Will the laser hurt?

Before the laser is applied, local anaesthetic drops are put on the eye to numb it and drops instilled to dilate the pupil. This allows a contact lens held by the doctor to be placed against the eye. The contact lens helps keep the lids open while allowing the doctor to view the back of the eye in greater detail. Sometimes a dull thud sensation or occasionally a sharp pain is felt. Any discomfort experienced the same evening can be relieved by taking your usual painkiller and resting. If pain is still persistent after 24 hours please seek further advice.

Will the laser treatment affect my sight?

Yes. Immediately and for a few minutes afterwards you will be completely dazzled by the light. Later on vision can be blurred temporarily due to effects of the dilating drops. Changes may occur in colour vision, night vision and in the field of vision – the range of vision you have on each side of an object on which your gaze is fixed. On very rare occasions vision can be made worse. It is rare for the effect on colour vision to be a problem.

What happens after the laser treatment?

Most disease is controlled but may require more laser treatment. You will have regular eye checks to determine this. In some patients where there has been recurrent bleeding and the vitreous is clouded with blood, or a retinal detachment is present, a vitrectomy operation may be necessary.

Operation (vitrectomy)

By using delicate instruments and an operating microscope, the vitreous is removed by cutting it and sucking it out and replacing this with a clear substance (usually a form of saline, air, gas or silicone fluid). Very fine stitches are used to close the wound and do not need removal. There is a common myth that the eye is removed during surgery. Of course this can never be done, because the eye is physically connected to the socket by the optic nerve and muscles.

Will the operation allow me to see properly again?

This exchange of a clear substance for cloudy vitreous allows light to reach the retina again and can help to restore some vision but the quality of your vision may not be as good as it was previously. Sight may take weeks or months to improve. In some severe diabetic retinopathy success means stabilising the vision, that is, preventing it from getting worse. Further information about vitrectomy is available. Please ask if you require this.

>Close General Questions

What should I do if I see blood in my vision?

Don’t bend so that your head is below your heart and avoid any strenuous activity.

Can I continue to drive with diabetic retinopathy?

The UK law requires you to inform the Driver and Vehicle Licensing Agency (DVLA) and your motor insurance company of any change in health or sight likely to affect the safety of your driving. You must be able to read a number plate at 20.3m (25 yards) in good daylight and with spectacles if worn. You must also have an adequate field of vision. To drive when unable to meet both these requirements is a criminal act and invalidates insurance. Inability to meet these standards requires YOU to notify the DVLA. You should NOT drive until you have had confirmation that your vision meets the standards. A report may be requested from your ophthalmologist. Standards are more stringent for vocational drivers. Further details can be found on the DVLA website here: Medical rules for driving

What other help is available?

Low vision aids (usually magnifying devices) can enable most patients, who can count their fingers when held up, to continue to perform normal everyday tasks such as reading large newsprint, price tickets or road signs. They may be very simple hand held magnifiers or more complex electronic devices.

The social workers in the Moorfields Medcial Social Work Department are available to provide counselling and advice about education, training, employment, aids to daily living and registration as partially sighted or blind. Registration can benefit a minority of patients with retinopathy too advanced for effective treatment. This is not compulsory but the social security and other benefits might improve the quality of life.

Further information on diabetes can be obtained from:

The British Diabetic Association
10 Queen Anne Street
London W1M 0BD
Tel: 020 7323 1531

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You do not need a referral to see a Moorfields Private consultant. If you know which consultant you would like to see, please contact their private secretary to make an appointment or receive further information, or email us at enquiries@moorfields-private.co.uk

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